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Platform for Connectomics Research

Explore large-scale neural wiring diagrams and 3D reconstructions in the browser

Connectome Exploration Workspace

Connectome Exploration Workspace

Neuroglancer, cells table and network graph side by side.

Connectome Exploration Workspace
Features

Enabling Global Scientific Collaboration

Transform raw EM volumes and segmentation data into accessible, scientific workspaces. Build consensus, allow browser-based visualization, and bridge resources across international teams.

Remote Dataset Exploration

Zero-install web-based exploration, rendering, and interaction with massive petabyte-scale 3D volume, segmentation, and synapse datasets.

Comparative Connectomics

Explore neural circuits across species and within the same species.

Shareable Configurable Workspaces

Save, load, and share your exact workspace layout, visible neurons, camera viewpoints, and customized widget with their state with colleagues.

Advanced Tools

Special purpose workspaces enable powerful tools around cross-dataset mappings, finding genetic lines for your neurons of interest and more.

Public Version

Core widgets available to everyone for exploring public datasets

Neuroglancer 3D Viewer

Neuroglancer 3D Viewer

Full-featured Neuroglancer integration for 3D connectome exploration.

Cells Table

Cells Table

Browse, filter, and edit the full cell annotation table.

Cell Network Graph

Cell Network Graph

Interactive Cytoscape.js graph of cell connectivity.

Cell Connections Table

Cell Connections Table

Tabular view of upstream/downstream synapse partners and counts.

Professional Version

Power connectomics research in your lab with advanced widgets and tools with the professional subscription

Connectome Chatbot

Connectome Chatbot

A large-language-model-powered chatbot that answers questions about the connectome dataset. It translates natural-language questions into database queries.

Grouped Network Graph

Grouped Network Graph

Aggregate connectivity graph grouped by cell type or class.

Video Editor

Video Editor

Create and export Neuroglancer keyframe animations as videos.

Skeleton Graph

Skeleton Graph

Computes a skeleton from the neuron mesh, maps synapses to skeleton nodes, and projects the 3D structure into 2D using a Maxent-Stress layout.

Connectivity Matrix

Connectivity Matrix

Renders a heatmap matrix of synapse counts with cell types or cell classes on both axes. Supports group-by selection and choice of colormaps.

Collaboration & Proofreading

Collaborative Proofreading Projects

Empower proofreaders, annotators, and researchers to correct reconstruction errors and build high-quality wiring diagrams. Track daily edits, share progress, and coordinate edits directly on CAVE-enabled datasets.

Segmentation Proofreading Workflows

Tools for visual verification, tracking workspace changes, segment isolation, and validation of cell reconstruction.

User Accounts and Permission

Role-based access controls to securely manage workspace layouts, edit permissions, and database operations.

Integration with CAVE

Robust connection with Connectome Annotation Version Engine backend for dynamic, real-time revision of segmentation states.

Synapse Annotations and Review

Tools to dynamically query, highlight, review, and manually verify pre- and post-synaptic sites directly in 3D.

Volume Annotations (WiP)

Upcoming features to interactively paint, fix, and annotate 3D voxels for rapid mesh edits and localized proofreading.

Supporting Cell Typing (WiP)

Structured workflows to categorize, tag, and assign cell classifications based on morphology, connectivity, and reference atlases.

Widgets for Proofreading Workflows

Specialized interfaces for identifying segmentation errors, validating connections, and managing annotation tables

Orphan Table

Orphan Table

Lists orphan segments — neurite fragments that have synaptic connections but have not yet been assigned to a named cell.

Cell Annotations

Cell Annotations

Create and manage point/line annotations with Neuroglancer integration, syncing annotations between Neuroglancer and the backend.

Connection Review

Connection Review

Enables targeted review of synaptic connections between sets of presynaptic and postsynaptic cells to target proofreading effort.

CAVE Annotation Tables

CAVE Annotation Tables

Get an overview of available annotation tables in CAVE, with support for filtering, sorting, searching, and jumping to coordinate states.

Progress Statistics

Progress Statistics

Fetches proofreading edit history from the backend and displays the number of edits per day as a bar chart to track progress over time.

Chat Widget

Chat Widget

A real-time chat widget for general discussion, collaborative note-taking, and community questions about shared datasets.